Web based lecture technologies: blurring the boundaries between face to face and distance learning

Web based lecture technologies (WBLT) have gained popularity amongst universities in Australia as a tool for delivering lecture recordings to students in close to real time. This paper reports on a selection of results from a larger research project investigating the impact of WBLT on teaching and learning. Results show that while staff see the advantages for external students, they question the extent to which these advantages apply to internal students. In contrast both cohorts of students were positive about the benefits of the technologies for their learning and they adopted similar strategies for their use. With the help of other technologies, some external students and staff even found WBLT useful for fostering communication between internal and external students. As such, while the traditional boundary between internal and external students seems to remain for some staff, students seem to find the boundary much less clear

Promoting Service Learning Via Online Instruction

Service learning and online instruction are both important and much debated topics in higher education. Many professors and colleges are attempting to use service learning and online instruction as effective learning tools for their student clientele. Both topics are being written about exclusively in professional journals, as educators grapple with how lo implement these two effective means of learning into class content. The purpose of this manuscript is to discuss service learning and online instruction in a symbiotic educational relationship. The authors discuss the efficacy and benefits of service learning and online instruction, and request ways to incorporate these techniques into the classroom. A case example is presented to illustrate the application of these two techniques as they are combined to produce an effective online course that provides students with a hands-on learning experience

Portland’s Food Economy: Trends and Contributions

The primary goal of this report is to document the scope, growth, and contribution of the food economy to the city of Portland and the region. Specifically, this report addresses the following research questions: What is the food economy, and how is it defined? What is the size of Portland’s food economy, and how has it changed in recent years? How is the food economy distributed spatially within the city and the region? How is this changing? What kind of employment opportunities does Portland’s food economy offer? How do they compare to the broader economy? Who works in Portland’s food economy? How has Portland’s food economy performed relative to national trends? What is the broader impact and contribution of the Portland food economy to the overall regional economy, and to state and local government finances

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

CBS domains are defined as sequence motifs that occur in several different proteins in all kingdoms of life. Although thought to be regulatory, their exact functions have been unknown. However, their importance was underlined by findings that mutations in conserved residues within them cause a variety of human hereditary diseases, including (with the gene mutated in parentheses): Wolff-Parkinson-White syndrome (γ2 subunit of AMP-activated protein kinase); retinitis pigmentosa (IMP dehydrogenase-1); congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members); and homocystinuria (cystathionine β-synthase). AMP-activated protein kinase is a sensor of cellular energy status that is activated by AMP and inhibited by ATP, but the location of the regulatory nucleotide-binding sites (which are prime targets for drugs to treat obesity and diabetes) was not characterized. We now show that tandem pairs of CBS domains from AMP-activated protein kinase, IMP dehydrogenase-2, the chloride channel CLC2, and cystathionine β-synthase bind AMP, ATP, or S-adenosyl methionine,while mutations that cause hereditary diseases impair this binding. This shows that tandem pairs of CBS domains act, in most cases, as sensors of cellular energy status and, as such, represent a newly identified class of binding domain for adenosine derivatives

Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives

Gastrointestinal motility research is progressing rapidly, leading to significant advances in the last 15 years in understanding the cellular mechanisms underlying motility, following the discovery of the central role played by the interstitial cells of Cajal (ICC). As experimental knowledge of ICC physiology has expanded, biophysically based modeling has become a valuable tool for integrating experimental data, for testing hypotheses on ICC pacemaker mechanisms, and for applications in in silico studies including in multiscale models. This review is focused on the cellular electrophysiology of ICC. Recent evidence from both experimental and modeling domains have called aspects of the existing pacemaker theories into question. Therefore, current experimental knowledge of ICC pacemaker mechanisms is examined in depth, and current theories of ICC pacemaking are evaluated and further developed. Existing biophysically based ICC models and their physiological foundations are then critiqued in light of the recent advances in experimental knowledge, and opportunities to improve these models are identified. The review concludes by examining several potential clinical applications of biophysically based ICC modeling from the subcellular through to the organ level, including ion channelopathies and ICC network degradation

Constructions of Generalized Sidon Sets

We give explicit constructions of sets S with the property that for each integer k, there are at most g solutions to k=s_1+s_2, s_i\in S; such sets are called Sidon sets if g=2 and generalized Sidon sets if g\ge 3. We extend to generalized Sidon sets the Sidon-set constructions of Singer, Bose, and Ruzsa. We also further optimize Koulantzakis' idea of interleaving several copies of a Sidon set, extending the improvements of Cilleruelo & Ruzsa & Trujillo, Jia, and Habsieger & Plagne. The resulting constructions yield the largest known generalized Sidon sets in virtually all cases.Comment: 15 pages, 1 figure (revision fixes typos, adds a few details, and adjusts notation

Opening dialogue and fostering collaboration: different ways of knowing in fisheries research

We set out to explore some of the impediments which hinder effective communication among fishers, fisheries researchers and managers using detailed ethnographic research amongst commercial handline fishers from two sites- one on the southern Cape coast and the other on the west coast of South Africa. Rather than assuming that the knowledge of fishers and scientists is inherently divergent and incompatible, we discuss an emerging relational approach to working with multiple ways of knowing and suggest that this approach might benefit future collaborative endeavours. Three major themes arising from the ethnographic fieldwork findings are explored: different classifications of species and things; bringing enumerative approaches into dialogue with relational approaches; and the challenge of articulating embodied ways of relating to fish and the sea. Although disconcertments arise when apparently incommensurable approaches are brought into dialogue, we suggest that working with multiple ways of knowing is both productive and indeed necessary in the current South African fisheries research and management contexts. The research findings and discussion on opening dialogue offered in this work suggest a need to rethink contemporary approaches to fisheries research in order to mobilise otherwise stagnant conversations, bringing different ways of knowing into productive conversation